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 Gene Protein Single-nucleotide polymorphism Enzyme inhibitor Chemotherapy CYP3A4 Allele ATP-binding cassette transporter Verapamil Pharmacokinetics P-glycoprotein DNA Polymerase chain reaction Messenger RNA Acid Western blot Apoptosis Zygosity Radiation therapy Breast cancer Neoadjuvant therapy Metastasis Carcinoma Cytochrome P450 CYP2C9 Drug metabolism CYP2D6 Lipid Calcium Calcium channel blocker Umbilical vein Blood plasma Bioavailability Biological half-life Pharmacodynamics
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Gene  12 times
Protein  10 times
Single-nucleotide polymorphism  8 times
Enzyme inhibitor  8 times
Chemotherapy  6 times
CYP3A4  6 times
Allele  6 times
ATP-binding cassette transporter  6 times
Verapamil  5 times
Pharmacokinetics  5 times
Paclitaxel  5 times
Immunohistochemistry  5 times
Flow cytometry  5 times
Western blot  4 times
Real-time polymerase chain reaction  4 times
Doxorubicin  4 times
DNA  4 times
Cisplatin  4 times
CYP2C19  4 times
Apoptosis  4 times
Platelet  3 times
Ovarian cancer  3 times
Methotrexate  3 times
Metabolite  3 times
Messenger RNA  3 times
Mechanistic target of rapamycin  3 times
Cytochrome P450  3 times
Clopidogrel  3 times
Cell cycle  3 times
Breast cancer  3 times
Blood plasma  3 times
Zygosity  2 times
Xenobiotic  2 times
Systemic lupus erythematosus  2 times
Small interfering RNA  2 times
Sirolimus  2 times
Rivaroxaban  2 times
Rheumatoid arthritis  2 times
Protein Data Bank  2 times
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Peripheral neuropathy  2 times
Percutaneous coronary intervention  2 times
Odds ratio  2 times
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Mouse  2 times
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G1 phase  2 times
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Cyclophosphamide  2 times
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Blood–brain barrier  2 times
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Acid  2 times
ABCG2  2 times
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PubMed  1 time
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Cyclin-dependent kinase  1 time
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Publications tagged with this subject: 45

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1. Unusual gastrointestinal and cutaneous toxicities by bleomycin, etoposide, and cisplatin: a case report with pharmacogenetic analysis to personalize treatment

2. Variability of platelet response to clopidogrel is not related to adverse cardiovascular events in patients with stable coronary artery disease undergoing percutaneous coronary intervention

3. Preparation and evaluation of self-microemulsions for improved bioavailability of ginsenoside-Rh1 and Rh2

4. ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report

5. Inhibition of mTOR Pathway by Rapamycin Decreases P-glycoprotein Expression and Spontaneous Seizures in Pharmacoresistant Epilepsy

6. Investigating the role of miRNA-98 and miRNA-214 in chemoresistance of HepG2/Dox cells: studying their effects on predicted ABC transporters targets

7. Determination of variations of the primary structure of the UGT1A1, DPYD, GSTP1, and ABCB1 genes involved in the metabolism of antitumor agents

8. Role of the OATP Transporter Family and a Benzbromarone-SensitiveEfflux Transporter in the Hepatocellular Disposition of Vincristine

9. Neuroprotective effects of AT1 receptor antagonists after experimental ischemic stroke: what is important?

10. Clinical Pharmacokinetics and Pharmacodynamics of Panobinostat

11. ABCB1 and ABCG2 drug transporters are differentially expressed in non-small cell lung cancers (NSCLC) and expression is modified by cisplatin treatment via altered Wnt signaling

12. Molecular and structural characteristics of multidrug resistance-associated protein 7 in Chinese liver fluke Clonorchis sinensis

13. Selection of P-Glycoprotein Inhibitor and Formulation of Combinational Nanoformulation Containing Selected Agent Curcumin and DOX for Reversal of Resistance in K562 Cells

14. TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer

15. Association of ABCB1 promoter methylation with aspirin exposure, platelet function, and clinical outcomes in Chinese intracranial artery stenosis patients

16. Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer

17. Clinical relevance of P-glycoprotein activity on peripheral blood mononuclear cells and polymorphonuclear neutrophils to methotrexate in systemic lupus erythematosus patients

18. Influence of genetic co-factors on the population pharmacokinetic model for clopidogrel and its active thiol metabolite

19. Prognostic and predictive factors in patients with metastatic or recurrent cervical cancer treated with platinum-based chemotherapy.

20. The drug transporter ABCB1 c.3435C>T SNP influences artemether–lumefantrine treatment outcome

21. Virulence factors, antifungal susceptibility and molecular mechanisms of azole resistance among Candida parapsilosis complex isolates recovered from clinical specimens

22. No correlation between MTHFR c.677 C > T, MTHFR c.1298 A > C, and ABCB1 c.3435 C > T polymorphisms and methotrexate therapeutic outcome of rheumatoid arthritis in West Algerian population

23. The role of testosterone in the regulation of P-glycoprotein functioning

24. Sedative Effects of Levocetirizine: A Systematic Review and Meta-Analysis of Randomized Controlled Studies

25. The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary

26. Renal Drug Transporters and Drug Interactions

27. Kuguacin J isolated from bitter melon leaves modulates paclitaxel sensitivity in drug-resistant human ovarian cancer cells

28. P-glycoprotein gene MDR1 polymorphisms and susceptibility to systemic lupus erythematosus in Guangxi population: a case-control study

29. Molecular study of ABCB1 gene and its correlation with imatinib response in chronic myeloid leukemia

30. Inhibition of P-glycoprotein stimulates cell death under Hypoxia-mimicking conditions

31. Possible Role of microRNA-122 in Modulating Multidrug Resistance of Hepatocellular Carcinoma

32. Inhibition of CDK4 sensitizes multidrug resistant ovarian cancer cells to paclitaxel by increasing apoptosiss

33. Paclitaxel-induced sensory peripheral neuropathy is associated with an ABCB1 single nucleotide polymorphism and older age in Japanese

34. Polymorphism of the multidrug resistance 1 gene MDR1 G2677T/A (rs2032582) and the risk of drug-resistant epilepsy in the Polish adult population

35. Polymorphisms in the multidrug-resistance 1 gene related to glucocorticoid response in rheumatoid arthritis treatment

36. Effect of ketoconazole on the transport and metabolism of drugs in the human liver cell model

37. Contribution of tumor endothelial cells to drug resistance: anti-angiogenic tyrosine kinase inhibitors act as p-glycoprotein antagonists

38. Has time come for the use of direct oral anticoagulants in the extended prophylaxis of venous thromboembolism in acutely ill medical patients? Yes

39. Immaturity of Bile Canalicular–Ductule Networks in the Future Liver Remnant While Associating Liver Partition and Portal Vein Occlusion for Staged Hepatectomy (ALPPS)

40. Meta-analysis of effects of ABCB1 polymorphisms on clopidogrel response among patients with coronary artery disease

41. Pantoprazole Induces Apoptosis of Leukemic Cells by Inhibiting Expression of P-Glycoprotein/Multidrug Resistance-Associated Protein-1 Through PI3K/AKT/mTOR Signaling

42. Structure based classification for bile salt export pump (BSEP) inhibitors using comparative structural modeling of human BSEP

43. Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women

44. Strategies of Drug Transporter Quantitation by LC-MS: Importance of Peptide Selection and Digestion Efficiency

45. In Vitro Comparison of the Role of P-Glycoprotein and Breast Cancer Resistance Protein on Direct Oral Anticoagulants Disposition


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