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 BRCA1 Breast cancer Ovarian cancer Gene DNA DNA repair Polymerase Polymerase chain reaction P53 Mastectomy BRCA2 Estrogen receptor Chemotherapy Neu! Metastasis Protein Messenger RNA Acid Genome Cell cycle Metabolism Chain reaction Biochemical cascade Western blot Apoptosis Breast reconstruction Radiation therapy Lymph node
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Publications tagged with this subject: 35

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1. Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study

2. Efficacy versus effectiveness of clinical genetic testing criteria for BRCA1 and BRCA2 hereditary mutations in incident breast cancer

3. Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer

4. The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes

5. Preferences for breast cancer risk reduction among BRCA1/BRCA2 mutation carriers: a discrete-choice experiment

6. Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation

7. Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages

8. Monoallelic characteristic-bearing heterozygous L1053X in BRCA2 gene among Sudanese women with breast cancer

9. Germline BRCA mutations in Asian patients with pancreatic adenocarcinoma: a prospective study evaluating risk category for genetic testing

10. Analysis of BRCA1/2 mutation spectrum and prevalence in unselected Chinese breast cancer patients by next-generation sequencing

11. Our genes, our selves: hereditary breast cancer and biological citizenship in Norway

12. Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations

13. Assessment of in silico protein sequence analysis in the clinical classification of variants in cancer risk genes

14. Clinical Decision-Making in Patients with Variant of Uncertain Significance in BRCA1 or BRCA2 Genes

15. Exploiting Homologous Recombination Deficiency in TNBC

16. Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients

17. Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers

18. Cost Effectiveness of Risk-Reducing Mastectomy versus Surveillance in BRCA Mutation Carriers with a History of Ovarian Cancer

19. When to Consider Risk-Reducing Mastectomy in BRCA1/BRCA2 Mutation Carriers with Advanced Stage Ovarian Cancer: a Case Study Illustrating the Genetic Counseling Challenges

20. Prevalence and spectrum of germline rare variants in BRCA1/2 and PALB2 among breast cancer cases in Sarawak, Malaysia

21. The expected benefit of preventive mastectomy on breast cancer incidence and mortality in BRCA mutation carriers, by age at mastectomy

22. Identification and Characterization of a New BRCA2 Rearrangement in an Italian Family with Hereditary Breast and Ovarian Cancer Syndrome

23. Video Education on Hereditary Breast and Ovarian Cancer (HBOC) for Physicians: an Interventional Study

24. Breast cancer risk models: a comprehensive overview of existing models, validation, and clinical applications

25. BRCA2 carriers with male breast cancer show elevated tumour methylation

26. Early-onset primary peritoneal carcinoma from atypical cells after risk-reducing salpingo-oophorectomy for BRCA2 mutation carrier: a case report

27. The role of screening MRI in the era of next generation sequencing and moderate-risk genetic mutations

28. Biallelic BRCA2 mutations in two black South African children with Fanconi anaemia

29. Breast cancer detection and tumor characteristics in BRCA1 and BRCA2 mutation carriers

30. Opportunistic Salpingectomy as an Ovarian Cancer Primary Prevention Strategy

31. The potential role of miRNAs in therapy of breast and ovarian cancers associated with BRCA1 mutation

32. Inherited DNA repair gene mutations detected by tumor next generation sequencing in urinary tract cancers

33. Next-generation sequencing in familial breast cancer patients from Lebanon

34. Ganetespib overcomes resistance to PARP inhibitors in breast cancer by targeting core proteins in the DNA repair machinery

35. Prevalence of two BRCA1 mutations, 5382insC and 300T > G, in ovarian cancer patients from Ukraine


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